Proteoforms, the diverse molecular variants of proteins, are key to understanding cellular functions, disease mechanisms, and ...

Post-translational modifications (PTMs) of tubulin, including acetylation, glutamylation and detyrosination, play a critical role in dictating the dynamic behaviour and specialised functions of ...

Tuberculosis is still one of the deadliest infectious diseases, causing over one million deaths each year worldwide. Additionally, about one-fourth of the world's population carries Mycobacterium ...

Whole blood derived from six adult donors who were inoculated with BCG in their childhood was cultured with MDP1 alone, MDP1 in combination with G9.1, or in combination with the negative form of ...

Non-CHO cell expression systems gain traction as faster, more flexible alternatives for biologics manufacturing.

A new study led by Nicolás Bologna, a CSIC researcher at the Center for Research in Agricultural Genomics (CRAG), sheds light on the crucial role of the N-terminal extension (NTE) of AGO proteins, ...

Explore how proteomics enables personalized medicine by improving patient stratification, treatment response, and diagnostics ...

A molecular model showing three of the main epigenetic modifications of DNA (orange) and histones (dark blue) [JUAN GAERTNER/Science Photo Library/Getty Images] Post-translational modifications (PTMs) ...

This multidisciplinary project integrates computational biology, structural modelling, population genomics, and AI. It will provide new mechanistic insights into how coding variation and PTMs ...

Researchers at Baylor College of Medicine have developed an artificial intelligence (AI) model that reveals how protein modifications link genetic mutations to disease. The method, called DeepMVP and ...