A remarkably small bacterium containing fewer than 500 genes serves as the basis for one of the most detailed digital life ...

By simulating the life cycle of a minimal bacterial cell—from DNA replication to protein translation to metabolism and cell ...

The story of life’s beginnings gets stranger when you look closely at viruses. These tiny entities seem to sit at the edge of ...

A giant DNA virus pulled from a Japanese freshwater pond is forcing scientists to rethink how complex cells first acquired their defining feature: the nucleus. Named ushikuvirus, the newly ...

A team of researchers at VCU Massey Comprehensive Cancer Center has identified a new pathway through which mutations in the tumor suppressor p53 gene—found very frequently in human tumors—hijack DNA ...

A fleeting DNA fold called i‑DNA can switch cancer‑related genes on and off, revealing a hidden structural weak point that future therapies might exploit to collapse tumors.

DNA replication is a fundamental process essential for bacterial growth and survival. Initiation begins at the chromosomal origin (oriC), where the conserved initiator protein DnaA assembles into an ...

The DNA packed inside every human cell contains instructions for life, written in billions of letters of genetic code. Every time a cell divides, the complete code, divided among 46 chromosomes, must ...

The MCM helicase is broadly bound across the genome, and its phosphorylation is antagonistically regulated by the kinase DDK and the phosphatase RIF1–PP1. TRESLIN–MTBP recognises the phosphorylated ...

King Abdullah University of Science & Technology (KAUST)Mar 19 2025 For the first time, scientists have witnessed the very moment DNA begins to unravel, revealing a necessary molecular event for DNA ...

This transcript has been edited for clarity. For more episodes, download the Medscape app or subscribe to the podcast on Apple Podcasts, Spotify, or your preferred podcast provider. Dr Liu is a ...