It has long been accepted that a gene's protein-coding information is contained in only one of its two DNA strands. But in 22 February Nature, Victor Corces and co-workers at the Department of Biology ...

How does the cell convert DNA into working proteins? The process of translation can be seen as the decoding of instructions for making proteins, involving mRNA in transcription as well as tRNA. But ...

DNA-to-protein mapping could help researchers understand some health disparities. A new genetic mapping study led by researchers at the Johns Hopkins Bloomberg School of Public Health traces links ...

Non-coding DNA is essential for both humans and trypanosomes, despite the large evolutionary divergence between these two species.

The origins of millions of tiny proteins in our bodies, previously assumed to be useless, have now been discovered. A study published on February 17 in the journal Molecular Cell describes how these ...

Plasmids, small circular DNA molecules found in bacteria, may contain antibiotic-resistance genes and have the ability to replicate independently. Bacteria can transfer these plasmids to one another, ...

EMBL researchers created SDR-seq, a next-generation tool that decodes both DNA and RNA from the same cell. It finally opens access to non-coding regions, where most disease-associated genetic variants ...

Maintaining genomic integrity is the primary focus of DNA repair proteins. Though scientists have been able to elucidate many of the underlying mechanisms in complex repair pathways, how proteins can ...