The Flagship Pioneering spinout uses permanent bonds to target shallow pockets, drastically expanding the druggable universe for small molecules.

Terremoto Biosciences is a company making waves in the drug development world. They’re using a pretty cool approach to create new medicines, focusing on how molecules interact at a chemical level.

Covalent inhibitors are a specialized class of small molecules designed to form chemical bonds with their target proteins, often resulting in prolonged target engagement and enhanced potency. The ...

This video explores the limits of cutting paper, focusing on its primary component, cellulose. It analyzes the types of bonds that hold paper fibers together, including covalent bonds, hydrogen bonds, ...

Novartis is serving up $60 million to partner with Matchpoint Therapeutics in hopes of getting an oral covalent inhibitor over the line for inflammatory diseases that have been historically difficult ...

Numerous applications of phenolic compounds, a large family of naturally occurring molecules, in biosensing, bioimaging, and disease treatment can not be ...