As immune cells of the central nervous system (CNS), microglia constantly survey the brain and spinal cord for changes to the local environment. In response to CNS infection or injury, microglia ...

For the immune system to effectively combat pathogens, antibody responses must be precisely controlled. So-called follicular ...

An MUSC research team reports in Cells that the complement system, part of the body's natural immune defenses, is a key driver of inflammatory responses that contribute to fetal brain inflammation and ...

The immune response to Plasmodium falciparum malaria encompasses a complex interplay between innate and adaptive systems, tailored to each stage of the parasite’s life cycle. During the ...

Researchers at Hospital for Special Surgery (HSS) have uncovered a critical link between the immune system in early life and ...

Harvard Medical School scientists have identified a key protein in the human immune system that drives inflammatory and autoimmune conditions when it turns against the body. The protein, Granzyme K, ...