Medscape

Defining the COX Inhibitor Selectivity of NSAIDs: Implications for Understanding Toxicity

BAE: Bovine aortic endothelial; RHP: Recombinant human protein. NSAIDs variably inhibit prostaglandin H synthase (COX). COX-2 was cloned in 1991, and it was subsequently established that COX-1 does ...
Medscape

Efficacy and Tolerability of Meloxicam, a COX-2 Preferential Nonsteroidal Anti-Inflammatory Drug

Meloxicam is an enolcarboxamide with preferential COX-2 inhibitory activity. In vitro studies with human tissues have confirmed the high affinity of meloxicam for COX-2, whereas COX-1 was inhibited ...
Kitsap Sun

Use caution with pain relievers, even when they come over-the-counter

When people think of harmful pain medications, opioids are often the first drugs that come to mind. The damage these medications can cause has been the topic of news segments, magazine articles, and ...
Hosted on MSN

Should You Limit or Avoid Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) With Crohn’s Disease?

When cramping and abdominal pain from Crohns disease feels unmanageable, you may want to take pain medicine for relief. Nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen (Advil) and ...