(A) The diagram illustrates the destabilization of the medial meniscus (DMM) surgical process. Six-week-old male C57BL/6J mice underwent DMM surgery on the medial meniscus of the left hind limb. The ...
We’ve long blamed osteoarthritis on “wear and tear,” the price of a life well-lived. But could the cause be a more ancient culprit: a misfired developmental program that once built our skeletons and ...
"Historically viewed as mainly a “wear and tear” condition, new insights suggest that OA may be part of an evolutionary, age-related biological process rather than mainly driven by mechanical damage." ...