A research team led by investigators at McMaster University has identified an axonal guidance signaling pathway that cancer cells use to infiltrate the brain. The combined results of preclinical in ...

A hallmark of Parkinson's disease is the buildup of Lewy bodies—misfolded clumps of the protein known as alpha-synuclein.

A cross-sectional image of the mouse cerebral cortex in enlargement. The same method was applied as in the ferret. The cerebral cortex is shown in blue and some neurons are dyed green with GFP. In ...

Neurotrophins are essential proteins that support the growth, survival, and differentiation of neurons. Among these, brain-derived neurotrophic factor (BDNF) plays a crucial role in neuronal signaling ...

A new pathway that is used by cancer cells to infiltrate the brain has been discovered by a team of Canadian and American research groups led by the Singh Lab at McMaster University. The research also ...

Dopamine—a neurotransmitter responsible for influencing motivation, pleasure, mood and learning in the brain—has experienced ...