Nature

Exon-level array CGH in a large clinical cohort demonstrates increased sensitivity of diagnostic testing for Mendelian disorders

Mendelian disorders are most commonly caused by mutations identifiable by DNA sequencing. Exonic deletions and duplications can go undetected by sequencing, and their frequency in most Mendelian ...
Nature

Custom oligonucleotide array-based CGH: a reliable diagnostic tool for detection of exonic copy-number changes in multiple targeted genes

The frequency of disease-related large rearrangements (referred to as copy-number mutations, CNMs) varies among genes, and search for these mutations has an important place in diagnostic strategies.
Medscape

Molecular Diagnosis of Leukemia

Comparative genomic hybridization (CGH) is used to compare the genetic material from a test individual, such as a leukemia patient, to that of a reference 'normal' individual (usually DNA pooled from ...
GEN

CGH Sheds Its Light on Disease Etiology

Array comparative genomic hybridization (CGH) is illuminating DNA copy number variations (CNV) throughout the genome to diagnose disease etiology and to help tailor treatment regimens for patients to ...
GEN

Improving LOH Detection on CGH Microarrays

Due to its higher resolution, oligo array CGH has recently made strong inroads in the cytogenetic lab. It’s not surprising. With an increased sensitivity of more than 1,000-fold, microarrays can ...
technologynetworks

Agilent Technologies’ Custom-Designed CGH Microarray Used to Map Korean Genome

Agilent Technologies Inc. has announced that scientists using an Agilent custom-designed comparative genomic hybridization (CGH) array have sequenced the entire gene map of a Korean male. An ...